Systemic Overexpression of GDF5 in Adipocytes but Not Hepatocytes Alleviates High-Fat Diet-Induced Nonalcoholic Fatty Liver in Mice

<div>Normalized expression of NAFLD-related genes in LO2 cells. LO2 cells were transfected with a GDF5 overexpression lentivirus. (a) qPCR analysis of inflammation-related genes before FFA treatment. (b) qPCR analysis of inflammation-related genes after FFA treatment. (c) qPCR analysis of lipid metabolism-related genes before and (d) after FFA treatment. 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Canadian Journal of Gastroenterology and Hepatology

fig5

Figure 5

Figure 5: Systemic Overexpression of GDF5 in Adipocytes but Not Hepatocytes Alleviates High-Fat Diet-Induced Nonalcoholic Fatty Liver in Mice 