LncRNA PVT1 Promotes Cell Proliferation, Invasion, and Migration and Inhibits Cell Apoptosis by Phosphorylating YAP

Figure 5

The relationship among PVT1, YAP, and EMT in GC. PVT1 and YAP were both upregulated in GC tissues. In GC, PVT1 promotes the expression of YAP, inhibits the expression of p-YAP, promotes tumor cell proliferation, tumor cell migration, and invasion, and inhibits cell apoptosis. The increased expression of PVT1 promotes EMT.