Albumin Paclitaxel Compared with 5-Penfluorouracil, Lobaplatin, and Albumin Paclitaxel Combined with 5-Penfluorouracil in the Treatment of Human Gastric Cancer Cell AGS Line Autophagy and Apoptosis

Figure 2

Apoptosis in each group of AGS cells. (a) The 24 h apoptosis map of control; (b) the 24 h apoptosis map of Nab-PTX(0.2 μmol/l); (c) the 24 h apoptosis map of 5-F(2 μmol/l); (d) the LBP(10umol/l) 24 h apoptosis map; (e) the 24 h apoptosis map of Nab-PTX + 5-Fu (0.2 μmol/l + 2 μmol/l); (f) apoptotic cells (%) in different groups, analyzed by Annexin V-FITC/PI and using flow cytometry, Q1 = mechanical damage, Q2 = late apoptotic cells, Q3 = live cells, Q4 = early apoptotic cells. All the above experiments were repeated at least three times independently. , . Nab-PTX, 5-Fu, LBP, and Nab-PTX + 5-Fu can block the cell cycle at different stages.

(a)

(b)

(c)

(d)

(e)

(f)