Canadian Journal of Infectious Diseases and Medical Microbiology

Canadian Journal of Infectious Diseases and Medical Microbiology / 1992 / Article

Original Article | Open Access

Volume 3 |Article ID 837029 | https://doi.org/10.1155/1992/837029

Louise Deschênes, Jean R Joly, Michel Couillard, Gilles Richer, "Seroprevalence of Antibodies against Human Herpesvirus 6 in the Quebec City Area", Canadian Journal of Infectious Diseases and Medical Microbiology, vol. 3, Article ID 837029, 6 pages, 1992. https://doi.org/10.1155/1992/837029

Seroprevalence of Antibodies against Human Herpesvirus 6 in the Quebec City Area

Received22 Nov 1990
Accepted10 Jul 1991

Abstract

Seroprevalence of antibodies against human herpesvirus 6 was determined in a sample of 303 randomly selected individuals from the Quebec City area. The influence of different variables on antibody litres was also evaluated. Human herpesvirus 6 was grown in the HSB-2 cell line, and antibody litres were measured by indirect immunofluorescence. Serum samples were collected from 177 females and 126 males ranging in age from two months to 88 years. Ninety-nine per cent (300 of 303) of this population had an antibody titre of at least 1:10, whereas 75% had a titre of at least 1:80. Women had a higher geometric mean litre than men (P=0.06). This difference between sexes varied according to age and became statistically significant in subjects older than 20 years of age (P=0.04). It was found that this difference was attributable to higher antibody litres in women in the 15 to 40 year age group who had previously had children.

Copyright © 1992 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


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