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Canadian Journal of Infectious Diseases
Volume 13, Issue 2, Pages 89-99
Original Article

Epstein-Barr Virus Infection in Transplant Recipients: Sumary of a Workshop on Surveillance, Prevention and Treatment

Upton Allen,1 Caroline Alfieri,2 Jutta Preiksaitis,3 Atul Humar,4 Dorothy Moore,5 Bruce Tapiero,2 Raymond Tellier,6 Michael Green,7 Dele Davies,8 Diane Hébert,9 Sheila Weitzman,10 Martin Petric,6 Kevan Jacobson,11 and Canadian PTLD Workshop Group #x2013; 1999

1Division of Infectious Diseases, The Hospital for Sick Children, Toronto, Ontario, Canada
2Hôpital Ste-Justine, Montreal, Québec, Canada
3Division of Infectious Diseases, University of Alberta, Edmonton, Canada
4Division of Infectious Diseases, The Toronto Hospital, Ontario, Canada
5Montreal Children’s Hospital, Québec, Canada
6Department of Paediatric Laboratory Medicine, The Hospital for Sick Children, Toronto, Ontario, Canada
7University of Pittsburgh, Pennsylvania, USA
8Division of Infectious Diseases, University of Calgary, Alberta, Canada
9Division of Nephrology, The Hospital for Sick Children, Toronto, Ontario, Canada
10Division of Haematology/Oncology, The Hospital for Sick Children, Toronto, Ontario, Canada
11British Columbia’s Children’s Hospital, Vancouver, Canada

Received 19 July 2001; Revised 15 October 2001

Copyright © 2002 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Diseases caused by the Epstein-Barr virus are of great significance among organ transplant recipients. One of these diseases, post-transplant lymphoproliferative disease, is a major complication among organ transplant recipients. Management of this entity is problematic due to the difficulties with laboratory surveillance, diagnosis, prevention and treatment. A group of Canadian and American experts was assembled to discuss these aspects of Epstein-Barr virus diseases in Canadian organ transplant recipients. This report summarizes the relevant background literature and levels of evidence in relation to the outcomes of the deliberations and recommendations by the expert panel.