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Canadian Journal of Infectious Diseases and Medical Microbiology
Volume 19, Issue 4, Pages 309-310
Case Report

Case Report and Review of the Literature: Toxoplasma gondii Encephalitis in a 40-Year-Old Woman with Common Variable Immunodeficiency and a New Diagnosis of Large Granular Lymphocytic Leukemia

Adam Hofmann,1 Gerasimos Zaharatos,2 and Mark Miller2

1Department of Internal Medicine, McGill University, Canada
2Division of Infectious Diseases, Department of Medicine, SMBD-Jewish General Hospital, Montreal, Quebec, Canada

Received 25 September 2007; Accepted 10 April 2008

Copyright © 2008 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Toxoplasma gondii has been well-documented to cause central nervous system infections in immunodeficient patients. The present study describes a case of central nervous system toxoplasmosis in a patient with common variable immunodeficiency and newly diagnosed large granular lymphocytic leukemia, with a review of the literature for this association.