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Canadian Journal of Infectious Diseases and Medical Microbiology
Volume 20, Issue 3, Pages e100-e102
http://dx.doi.org/10.1155/2009/124173
Case Report

Human Granulocytic Anaplasmosis: First Reported Case in Canada

Michael D Parkins,1 Deirdre L Church,1,2,3 Xiu Yan Jiang,3 and Daniel B Gregson1,2,3

1Department of Medicine, University of Calgary, Canada
2Department of Pathology and Laboratory Medicine, University of Calgary, Canada
3Calgary Laboratory Services, Calgary, Alberta, Canada

Copyright © 2009 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Human granulocytic anaplasmosis (HGA) is a tick-borne rickettsial infection of peripheral blood neutrophils caused by Anaplasma phagocytophilum. While this infection is increasingly recognized as endemic throughout much of the United States, no Canadian cases have been previously described, despite the agent being identified in Canadian ticks. Herein we present a case of HGA acquired in an urban Alberta centre. Canadian physicians must be aware of the possibility of tick-borne rickettsial diseases as etiology of fever in individuals presenting with leukopenia/lymphopenia, thrombocytopenia and elevated transaminases during periods of tick activity. Prompt recognition and treatment are important in minimizing resultant morbidity and mortality.