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Canadian Journal of Infectious Diseases and Medical Microbiology

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Canadian Journal of Infectious Diseases and Medical Microbiology / 2012 / Article

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Case Report | Open Access

Volume 23 |Article ID 138470 | https://doi.org/10.1155/2012/138470

Ryan Yu, Suzanne E Dale, Deborah Yamamura, Vida Stankus, Christine Lee, "Daptomycin-Nonsusceptible, Vancomycin-Intermediate, Methicillin-Resistant Staphylococcus aureus Endocarditis", Canadian Journal of Infectious Diseases and Medical Microbiology, vol. 23, Article ID 138470, 3 pages, 2012. https://doi.org/10.1155/2012/138470

Daptomycin-Nonsusceptible, Vancomycin-Intermediate, Methicillin-Resistant Staphylococcus aureus Endocarditis

Ryan Yu,1 Suzanne E Dale,2,3 Deborah Yamamura,2,3 Vida Stankus,4 and Christine Lee2,3

1Michael G DeGroote School of Medicine, McMaster University, Canada

2Hamilton Regional Laboratory Medicine Programme, St Joseph’s Healthcare, Canada

3Department of Pathology and Molecular Medicine, McMaster University, Canada

4Department of Pharmacy, Hamilton Regional Laboratory Medicine Programme, St Joseph’s Healthcare, Hamilton, Ontario, Canada

Abstract

Due to the emergence of Staphylococcus aureus with reduced vancomycin susceptibility, newer antibiotics, including daptomycin, have been used to treat methicillin-resistant S aureus infections. Daptomycin is a cyclic lipopeptide that is approved to treat S aureus bacteremia and right-sided endocarditis, and reports of S aureus with reduced susceptibility to daptomycin are infrequent. To our knowledge, the present report describes the first Canadian case of daptomycin-nonsusceptible, vancomycin-intermediate S aureus infection.

Copyright © 2012 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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