Table 2: Baseline assessment of coinfected patients.

TestComment

Viral hepatitis screensHCV antibody
Quantitative HCV RNA
HCV genotype
Hepatitis B surface antigenChronic HBV infection
Hepatitis B surface antibodyImmunity to HBV
Hepatitis B core antibody
Hepatitis A IgGIf negative, indicates need for HAV vaccine

Liver-relatedComplete blood countThrombocytopenia may indicate advanced liver disease
ALT, AST
ALP, GGT
Albumin, INR, and total bilirubinAbnormalities suggest advanced liver disease
Ultrasound
Fibroscan

Screens for other chronic conditions of liver diseaseAlpha-1-antitrypsin Alpha-1 antitrypsin deficiency
Antinuclear antibody, anti-smooth muscle antibodyAutoimmune hepatitis
Anti-mitochondrial antibodyPrimary biliary cholangitis
CeruloplasminWilson’s disease
Iron saturationHemochromatosis
Lipid ProfileFatty liver disease
TSHAutoimmune thyroiditis
Immunoglobulins A, G, and MAutoimmune hepatitis, primary biliary cholangitis, and alcoholic liver disease