CIHR Canadian HIV Trials Network Coinfection and Concurrent Diseases Core Research Group: 2016 Updated Canadian HIV/Hepatitis C Adult Guidelines for Management and Treatment

Table 2

Baseline assessment of coinfected patients.

	Test	Comment
Viral hepatitis screens	HCV antibody
	Quantitative HCV RNA
	HCV genotype
	Hepatitis B surface antigen	Chronic HBV infection
	Hepatitis B surface antibody	Immunity to HBV
	Hepatitis B core antibody
	Hepatitis A IgG	If negative, indicates need for HAV vaccine
Liver-related	Complete blood count	Thrombocytopenia may indicate advanced liver disease
	ALT, AST
	ALP, GGT
	Albumin, INR, and total bilirubin	Abnormalities suggest advanced liver disease
	Ultrasound
	Fibroscan
Screens for other chronic conditions of liver disease	Alpha-1-antitrypsin	Alpha-1 antitrypsin deficiency
	Antinuclear antibody, anti-smooth muscle antibody	Autoimmune hepatitis
	Anti-mitochondrial antibody	Primary biliary cholangitis
	Ceruloplasmin	Wilson’s disease
	Iron saturation	Hemochromatosis
	Lipid Profile	Fatty liver disease
	TSH	Autoimmune thyroiditis
	Immunoglobulins A, G, and M	Autoimmune hepatitis, primary biliary cholangitis, and alcoholic liver disease