Canadian Journal of Infectious Diseases and Medical Microbiology / 2016 / Article / Tab 2

Special Article

CIHR Canadian HIV Trials Network Coinfection and Concurrent Diseases Core Research Group: 2016 Updated Canadian HIV/Hepatitis C Adult Guidelines for Management and Treatment

Table 2

Baseline assessment of coinfected patients.


Viral hepatitis screensHCV antibody
Quantitative HCV RNA
HCV genotype
Hepatitis B surface antigenChronic HBV infection
Hepatitis B surface antibodyImmunity to HBV
Hepatitis B core antibody
Hepatitis A IgGIf negative, indicates need for HAV vaccine

Liver-relatedComplete blood countThrombocytopenia may indicate advanced liver disease
Albumin, INR, and total bilirubinAbnormalities suggest advanced liver disease

Screens for other chronic conditions of liver diseaseAlpha-1-antitrypsin Alpha-1 antitrypsin deficiency
Antinuclear antibody, anti-smooth muscle antibodyAutoimmune hepatitis
Anti-mitochondrial antibodyPrimary biliary cholangitis
CeruloplasminWilson’s disease
Iron saturationHemochromatosis
Lipid ProfileFatty liver disease
TSHAutoimmune thyroiditis
Immunoglobulins A, G, and MAutoimmune hepatitis, primary biliary cholangitis, and alcoholic liver disease

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