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Canadian Journal of Infectious Diseases and Medical Microbiology
Volume 2016, Article ID 7231805, 3 pages
http://dx.doi.org/10.1155/2016/7231805
Case Report

First Report of Clostridium lavalense Isolated in Human Blood Cultures

1Service de Microbiologie Médicale et Maladies Infectieuses, Centre Hospitalier Universitaire Dr. Georges-L.-Dumont, Moncton, NB, Canada E1C 2Z3
2Laboratoire de Santé Publique du Québec, Sainte-Anne-de-Bellevue, QC, Canada H9X 3R5
3Centre de Recherche en Infectiologie de l’Université Laval, Ville de Québec, QC, Canada G1V 4G2

Received 24 December 2015; Revised 27 April 2016; Accepted 19 May 2016

Academic Editor: José A. Oteo

Copyright © 2016 Richard Garceau et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

An 88-year-old man was admitted to the hospital with worsening malaise, fever, and weakness. Anaerobic blood culture bottles revealed the presence of an anaerobic, Gram-positive sporulated bacillus. Empirical antibiotherapy with intravenous piperacillin-tazobactam was initiated. The patient defervesced after four days and was switched to oral amoxicillin on his 6th day of antibiotic therapy and later discharged from the hospital. Four months later, he had recovered. The bacterium was initially identified as Clostridium butyricum using anaerobic manual identification panel. 16S rRNA gene sequence and phylogenetic analysis showed the bacterium to be Clostridium lavalense, a recently described species with no previously published case of isolation in human diagnostic samples so far. This is the first report of Clostridium lavalense isolation from human blood cultures. Further studies are needed in order to elucidate the role of Clostridium lavalense in human disease and its virulence factors.