Association between Accessory Gene Regulator Polymorphism and Mortality among Critically Ill Patients Receiving Vancomycin for Nosocomial MRSA Bacteremia: A Cohort Study

Table 1

Characteristics of the patients with MRSA bacteremia.

Variable	N (%)
Age years, mean (SD)	55.5 (17.2)
Female sex, number (%)	9 (45.0)
Type of underlying disease, number (%)
Diabetes mellitus	6 (28.6)
Malignancy	5 (23.8)
Cardiac failure	3 (14.3)
Chronic renal failure	3 (14.3)
Chronic obstructive pulmonary disease	2 (9.5)
HIV	2 (9.5)
APACHE II score, mean (SD)	24.3 (8.5)
Initial plasma CRP, mg/L, mean (SD)	178.6 (110.8)
Initial serum creatinine, g/dL, mean (SD)	1.7 (1.3)
Genotypic characteristic of blood isolates, number (%)
agr group
I	11 (52.4)
II	10 (47.6)
III	0 (0)
IV	0 (0)
SCCmec type
I	2 (9.5)
II	0 (0)
III	5 (23.8)
IV	3 (14.3)
ND	11 (52.4)
Overall in-hospital mortality, number (%)	14 (66.6)

Note. SD: standard deviation; CRP: C-reactive protein; agr: accessory gene regulator; SCCmec: staphylococcal cassette chromosome mec; ND: not determined.