Clinical and Mortality Risk Factors in Bloodstream Infections with Carbapenem-Resistant Enterobacteriaceae

Table 3

Univariate analysis for predictors of mortality caused by bloodstream infections with Enterobacteriaceae.

Clinical characteristics	Bloodstream infections with Enterobacteriaceae, n (%)		value
	Survival group (n = 110)	Mortality group (n = 38)
Gender (male)	55 (50.0)	20 (52.6)	0.780
Age	67.5 ± 20.0	73.9 ± 15.9	0.075
Community acquired	28 (25.5)	2 (5.3)	0.008
Admission to the ICU	10 (9.1)	20 (52.6)	<0.001
Long-term bedbound	50 (45.5)	30 (78.9)	<0.001
Medical institution admission history within 3 months	69 (62.7)	23 (60.5)	0.809
Underlying diseases
Cardiovascular disease	51 (46.4)	22 (57.9)	0.220
Cerebrovascular disease	54 (49.1)	24 (63.2)	0.134
Chronic respiratory disease	12 (10.9)	3 (7.9)	0.827
Chronic kidney disease	30 (27.3)	16 (42.1)	0.089
Diabetes mellitus	38 (34.5)	15 (39.5)	0.585
Malignant tumor	37 (33.6)	11 (28.9)	0.594
Anemia	77 (70.0)	36 (94.7)	0.002
Hypoalbuminemia	87 (79.1)	37 (97.4)	0.008
Lung infection	53 (48.2)	30 (78.9)	0.001
Urinary tract infection	60 (54.5)	14 (36.8)	0.060
Abdominal infection	9 (8.2)	10 (26.3)	0.009
Tracheotomy	22 (20.0)	11 (28.9)	0.253
Liver dysfunction	20 (18.2)	17 (44.7)	0.001
Invasive surgery before infection
Mechanic ventilation	10 (9.1)	20 (52.6)	<0.001
Central venous catheterization	20 (18.2)	27 (71.1)	<0.001
Indwelling urethral catheterization	41 (37.3)	29 (76.3)	<0.001
Sources of bloodstream infection
Catheter related	19 (17.3)	14 (36.8)	0.012
Respiratory system	25 (22.7)	12 (31.6)	0.277
Urinary tract	39 (35.5)	3 (7.9)	0.001
Others	27 (24.5)	9 (23.7)	0.915
Prior use of broad-spectrum antibiotics within 30 days	36 (32.7)	28 (73.7)	<0.001
Combined fungal infection	9 (8.2)	11 (28.9)	<0.001
Prior use of glucocorticoids within 30 days	4 (3.6)	15 (39.5)	0.007
CRE infection	9 (8.2)	17 (44.7)	<0.001
Total length of hospital stay	21.4 ± 13.2	22.7 ± 10.4	0.528

CRE: carbapenem-resistant Enterobacteriaceae; .