Cost-Effectiveness Analysis of Fosfomycin for Treatment of Uncomplicated Urinary Tract Infections in Ontario

Table 1

Cost of antibiotics and healthcare resources used for the treatment of uUTIs and the ranges tested in the sensitivity analyses.

Variable	Base case (CAD $)	Range tested (CAD $)	References
Fosfomycin	17.51	13.00–18.00	[23], Pharmastat
Sulfonamides	0.95	0.88–2.79	[23], Pharmastat
Fluoroquinolones	4.25	3.71–11.78	[23], Pharmastat
Nitrofurantoin	10.54	4.68–11.12	[23], Pharmastat
Hospitalization for pyelonephritis	6,918.15	4,842.71–8,993.60	OCCI, hypothesis of plausible range (±30% of base case)
Initial clinic visit	77.20	—	[24]
Follow-up clinic visit	45.90	—	[24]
Urine culture	45.00	—	Laboratoires Biron, oral communication, May 30 2016
Emergency visit	287.6	—	[24–26]

mergency MD cost ($97.60) + total cost for an emergency visit in Quebec in 2009, MD cost excluded ($190).