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Canadian Journal of Infectious Diseases and Medical Microbiology
Volume 2017 (2017), Article ID 9509604, 5 pages
Review Article

Pathogenicity of Virulent Species of Group C Streptococci in Human

Department of Microbiology, Jagiellonian University, Czysta 18, 31-121 Kraków, Poland

Correspondence should be addressed to Marta Kłos

Received 13 February 2017; Revised 24 April 2017; Accepted 21 May 2017; Published 12 June 2017

Academic Editor: Nahuel Fittipaldi

Copyright © 2017 Marta Kłos and Jadwiga Wójkowska-Mach. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Group C streptococci (GCS) are livestock pathogens and they often cause zoonotic diseases in humans. They are Gram-positive, in mostly β-hemolytic and facultative anaerobes. Because of their close evolutionary kinship with group A streptococci (GAS), GCS share many common virulence factors with GAS and cause a similar range of diseases. Due to the exchange of genetic material with GAS, GCS belong to bacteria that are difficult to be distinguished from group A streptococci; GCS are often treated in microbiological diagnostics as contamination of the culture. This report focuses mainly on the pathogenicity of virulent species of GCS and their association with human diseases. The condition that is most frequently quoted is pharyngitis. In this paper, the virulence factors have also been mentioned and an interesting link has been made between GCS and the pathogenesis of rheumatic diseases among the native people of India and Aboriginal populations.