Research Article

Clinical Utility of Rapid Pathogen Identification for Detecting the Causative Organisms in Sepsis: A Single-Center Study in Korea

Table 1

Baseline characteristics of the preintervention and postintervention groups.

VariablePreintervention group ()Postintervention group ()

Age (years)63.2 ± 14.066.4 ± 13.60.26
Male (sex)25 (63)30 (52)0.29
Comorbidity
 Diabetes8 (20)21 (36)0.08
 Chronic heart failure3 (8)10 (17)0.16
 Cerebrovascular accident2 (5)7 (12)0.30
 Chronic pulmonary disease2 (5)6 (10)0.47
 Liver cirrhosis3 (8)6 (10)0.73
 Chronic kidney disease3 (8)2 (3)0.40
 Malignancy18 (45)9 (16)0.001
No. of SIRS criteria met at ICU admission3.3 ± 0.73.4 ± 0.70.59
qSOFA score at ICU admission2.3 ± 0.52.3 ± 0.50.98
 Altered mentation28 (70)44 (76)0.52
 Respiratory rate ≥22 breaths/min32 (80)49 (85)0.57
 Systolic blood pressure ≤100 mmHg33 (83)42 (72)0.25
Within 72 h of ICU admission
 Mechanical ventilation24 (60)31 (53)0.52
 Neuromuscular blockers6 (15)14 (24)0.27
 Vasopressor use28 (70)40 (69)0.91
 Renal replacement therapy20 (50)18 (31)0.06
Source of bacteremia
 Respiratory17 (43)25 (43)0.95
 Intra-abdominal11 (28)15 (26)0.86
 Genitourinary4 (10)5 (9)>0.99
 Skin and soft tissue/bone and joint3 (8)10 (17)0.16
 Vascular catheter2 (5)4 (7)>0.99

The data are presented as mean ± standard deviation or number (percentage) of patients. values indicate the results of comparing the preintervention and postintervention groups by using Student’s t-, chi-squared, or Fisher’s exact tests. SIRS: systemic inflammatory response syndrome; qSOFA: quick Sequential Organ Failure Assessment; ICU: intensive care unit.