Clinical Outcomes of Extended-Spectrum Beta-Lactamase-Producing Enterobacteriaceae Infections with Susceptibilities among Levofloxacin, Cefepime, and Carbapenems
Table 1
Baseline characteristics.
Characteristics
Carbapenem (n = 66)
Cefepime (n = 21)
Levofloxacin (n = 26)
value
Demographics
Age (years), mean (SD)
69.5 (15.9)
67.5(10.5)
72.5 (12.8)
0.357
Gender
0.065
Female, n (%)
41 (62.1)
8 (38.1)
19 (70.4)
Male, n (%)
25 (37.9)
13 (61.9)
8 (29.6)
Comorbidity score, mean (SD)
14.7 (10.4)
10 (8.4)
14.4 (13.1)
0.213
Type of infection
Hospital acquired, n (%)
21 (31.8)
1 (4.8)
8 (29.6)
0.046
Healthcare associated,n (%)
21 (31.8)
6 (28.6)
10 (37)
0.814
Community acquired, n (%)
24 (36.4)
13 (61.9)
9 (33.3)
0.082
Source of infection
Catheter LSI, n (%)
0 (0)
1 (4.8)
0 (0)
0.109
Bacteremia, n (%)
4 (6.1)
2 (9.5)
3 (11.1)
0.684
Septic shock, n (%)
8 (12.1)
2 (9.5)
5 (18.5)
0.614
Intra-abdominal, n (%)
5 (7.6)
0 (0)
2 (7.4)
0.434
Pneumonia, n (%)
7 (10.6)
1 (4.8)
1 (3.7)
0.452
SSTI, n (%)
10 (15.2)
6 (28.6)
2 (7.4)
0.136
UTI, n (%)
44 (66.7)
12 (57.1)
19 (70.4)
0.618
Culture species
E. coli, n (%)
51 (77.3)
18 (85.7)
24 (88.9)
0.369
K. pneumoniae, n (%)
11 (16.7)
1 (4.8)
1 (3.7)
0.118
P. mirabilis, n (%)
15 (22.7)
5 (23.8)
0 (0)
0.024
Healthcare-associated infections = acquired in nursing resident or recent hospitalization.
