Research Article

Cryptococcal Meningitis: A Retrospective Cohort of a Brazilian Reference Hospital in the Post-HAART Era of Universal Access

Table 3

Laboratory findings of 79 patients with cryptococcal meningitis.

VariableInitialaAfter treatment value
Mean (range)Mean (range)

Opening pressure (cm H2O)30 (10–130)22 (10–50)0.387
CSF glucose (mg/dL)36.5 (1–145)43 (2–154)0.278
CSF leukocytes (cells/µL)25 (1–853)8 (0–300)<0.05
CSF proteins (mg/dL)82 (0–882)59 (0–1866)0.228

(%) (%)

CSF antigenb ≥1 : 1000(55.6)7 (8.8)0.642
CSF positive culture(93.6)6 (7.5)1.00
Blood culture positivec(45.5)
Blood antigen ≥1 : 1000b(40.5)
Bronchoalveolar lavage positive(7.5)

CSF, cerebrospinal fluid. aAfter 2-week course of induction therapy. bCryptococcus antigen. cCollected within 14-day period of induction therapy.