Research Article
Candida Bloodstream Infection: Changing Pattern of Occurrence and Antifungal Susceptibility over 10 Years in a Tertiary Care Saudi Hospital
Table 1
Patients general characteristics.
| | Item | Identified variables | N (%) |
| | Gender | Male | 173 (53.4) | | Female | 151 (46.6) | | Age | Mean ± SD | 49.7 ± 28.1 | | Place of isolation | Intensive care unit (ICU) | 219 (67.6) | | Medical | 49 (15) | | Others | 56 (17.3) | | Nonintensive care unit | 105 (32.4) | | Risk factors | Prior ICU admission | 195 (60.2) | | Neutropenia | 19 (5.9) | | Use of broad-spectrum antibiotic | 264 (81.5) | | Presence of vascular device | 188 (58) | | Internal jugular | 98 (30.2) | | Subclavian | 34 (10.5) | | Peripherally inserted central catheter (PICC) | 33 (10.2) | | Femoral | 64 (19.8) | | Parenteral nutrition | 60 (18.5) | | Intra-abdominal infection | 15 (4.6) | | Others (medications) | 44 (13.6) | | Candida species | C. albicans | 108 (33.3) | | Nonalbicans | 216 (66.7) | | C. tropicalis | 72 (22.2) | | C. glabrata | 60 (18.5) | | C. parapsilosis | 52 (16) | | C. krusei | 17 (5.2) | | Others | 15 (4.6) | | Drug susceptibility profile (susceptible) | Amphotericin B | 315 (97.2) | | Caspofungin | 314 (96.9) | | Fluconazole | 214 (66) | | Voriconazole | 281 (86.7) | | 14 days outcome | Alive | 215 (66.4) | | Dead | 109 (33.6) | | Hospital outcome | Alive | 134 (41.4) | | Dead | 190 (58.6) |
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= surgical 5.6%, cardiac 6.5%, and hematology 5.2%. |
