Rifabutin and Furazolidone Could Be the Candidates of the Rescue Regimen for Antibiotic-Resistant H. pylori in Korea
Table 1
The demographic characteristics of the patient with H. pylori strain ().
Characteristics
N (%)
Age, mean ± SD (years)
58.2 ± 10.3
Age >65 years, N (%)
13 (41.9%)
Men, N (%)
16 (51.6%)
Smoking, N (%)
6 (19.3%)
Drinking, N (%)
12 (38.7%)
Comorbidity
Diabetes mellitus type 2
2 (6.4%)
Hypertension
8 (25.8%)
Liver cirrhosis
1 (3.2%)
Cerebrovascular disorders
1 (3.2%)
Thyroid cancer
1 (3.2%)
Idiopathic pulmonary fibrosis
1 (3.2%)
Pulmonary tuberculosis
1 (3.2%)
Reasons for Helicobacter spp. cultures§
First-line or second-line empirical treatment failure
9 (29.0%)
Patients’ reported antibiotic uses history in 3 years
15 (48.4%)
Other clinically suspected medical condition of drug resistance¶
13 (41.9%)
Reason for eradication for H. pylori
Peptic ulcer disease
15 (48.4%)
Early gastric cancer
2 (6.5%)
MALToma
4 (12.9%)
Atrophic gastritis
10 (32.3%)
¶Other clinically suspected medical conditions of drug resistance; patients with old age more than 65 years who have had more chance to exposure into several antibiotics or patients with severe comorbid conditions such as congestive heart failure, liver cirrhosis, renal failure, autoimmune disorders, pulmonary disease, and so on. §Total sum of population is not 100% since duplication cases. NSAID, nonsteroidal anti-inflammatory drug; HTN, hypertension; PUD, peptic ulcer disease; EGC, early gastric cancer; MALToma, mucosa-associated lymphoid tissue lymphoma.
