Research Article

A Comparative Study of High-Dose Colistin Administration for the Management of Multidrug-Resistant Gram-Negative Infections in the ICU

Table 2

Clinical and microbiological response and toxicity comparison.

9 MIU daily, n (%)3 MIU TDS, n (%)Total, n (%) value

Clinical response13 (76.5%)14 (77.8%)27 (77.1%)0.999
Microbiological response8 (47.1%)11 (61.1%)19 (54.3%)0.404
AKI4 (23.52%)8 (44.44%)12 (34.28%)0.193
Time to increase Scr7 (7.5)4.5 (4.5)0.283
Time to response14 (3)14 (10)14 (6)0.720

Median day (IQR), AKI; acute kidney injury, IQR; interquartile range.