Research Article

The Predictive Effectiveness of Blood Biochemical Indexes for the Severity of COVID-19

Table 1

Baseline characteristics and laboratory findings of patients infected with 2019-nCoV on admission to hospital.

All patients (n = 108)Disease severity
Severe (n = 24)Nonsevere (n = 84)

Age
Median, year43.6154.4640.44

Distribution
 0–<14 yr4 (3.7%)04 (4.76%)
 ≥14–<40 yr42 (38.89%)2 (8.33%)40 (47.61%)
 ≥40–<65 yr48 (44.44%)16 (66.67%)32 (38.1%)
 ≥65 yr14 (12.96%)6 (25%)8 (9.52%)

Sex
 Male56 (51.85%)12 (50%)44 (52.38%)
 Female52 (48.15%)12 (50%)40 (47.62%)

Wuhan exposure
 Yes58 (53.7%)16 (66.67%)42 (50%)
 No50 (46.3%)8 (33.33%)42 (50%)

Comorbidities
 Yes35 (32.41%)17 (70.83%)18 (21.43%)
 No73 (67.59%)7 (29.17%)66 (78.57%)

Hypertension16 (14.81%)109 (41.67%)6 (7.14%)
Diabetes5 (4.63%)2 (8.33%)3 (3.57%)
Cerebral infarction4 (3.7%)3 (0.125%)1 (1.19%)
Respiratory disease3 (2.78%)2 (8.33%)1 (1.19%)
Liver disease10 (9.26%)4 (16.67%)6 (7.14%)

Symptoms
 Fever73 (67.59%)23 (95.83%)50 (59.52%)
 Cough52 (48.15%)13 (54.17%)39 (46.43%)
 Pharyngalgia15 (13.89%)2 (8.33%)13 (15.48%)
 Expectoration11 (10.19%)3 (12.5%)9 (10.71%)
 Dyspnea8 (7.41%)7 (29.17%)1 (1.19%)
 Dizziness5 (4.63%)2 (8.33%)3 (3.57%)
 Headache4 (3.7%)3 (12.5%)1 (1.19%)
 Weakness40 (37.04%)13 (54.17%)27 (32.14%)
 Myalgia12 (11.11%)6 (0.25%)6 (7.14%)
 Chills10 (9.26%)2 (8.33%)8 (9.52%)
 Diarrhea5 (4.63%)3 (12.5%)2 (2.38%)

Laboratory check (normal value)
White blood cell count (4–10 × 109/L)
 <439 (36.11%)6 (25%)33 (39.29%)
 ≥4–<1065 (60.19%)17 (70.83%)48 (57.14%)
 ≥104 (3.7%)1 (4.17%)3 (3.57%)

Lymphocyte ratio (20–40%)
 <2027 (25%)11 (45.83%)16 (19.05%)
 ≥20–≤4074 (68.52%)13 (54.17%)61 (72.62%)
 >407 (6.48%)07 (8.33%)

Lymphocyte count (0.8–4.0 × 109/L)
 <0.825 (23.15%)11 (45.83%)14 (16.67%)
 ≥0.8–≤4.081 (75%)13 (54.17%)68 (80.95%)
 >4.02 (1.85%)02 (2.38%)

CRP (0–8.0 mg/L)
 ≤832 (29.63%)032 (38.1%)
 >8–≤2026 (24.07%)7 (29.17%)19 (22.62%)
 >20–≤4029 (26.85%)6 (25%)23 (27.38%)
 >4021 (19.44%)11 (45.83%)10 (11.90%)

ESR (0–15 mm/h)n = 103n = 21n = 82
 ≤4054 (52.43%)5 (23.81%)49 (59.76%)
 >40–≤8039 (37.86%)13 (61.9%)26 (31.71%)
 >8010 (9.71%)3 (14.29%)7 (8.54%)