Research Article

Noninvasive Evaluation of Liver Fibrosis in a Sample of Putative Inactive HBV Carriers in Rome, Italy

Table 5

Relation between HBV-DNA and liver stiffness in the subgroup of 66 patients during the follow-up.

CharacteristicsHBV-DNA <2000 UI/mlHBV-DNA ≥2000 UI/ml value

Basal time
Liver stiffness (kPa)5.80 ± 2.29
 LS < 7.5 kPa, n (%)50 (100%)0 (0%)
 LS ≥ 7.5 kPa, n (%)16 (100%)0 (0%)

12 months
Liver stiffness (kPa)5.33 ± 1.226.79 ± 1.55<0.001
 LS < 7.5 kPa n (%)47 (87.0%)7 (13.0%)<0.001
 LS ≥ 7.5 kPa n (%)4 (33.3%)8 (66.7%)

24 months
Liver stiffness (kPa)5.30 ± 1.437.69 ± 1.07<0.0001
 LS < 7.5 kPa, n (%)51 (94.4%)3 (5.6%)<0.0001
 LS ≥ 7.5 kPa, n (%)5 (41.7%)7 (58.3%)

Continuous variable are expressed as mean ± standard deviation (SD). A value <0.05 is considered significant (Wilcoxon test). For categorical variables, a value <0.05 is considered significant (Fisher’s test).