Noninvasive Evaluation of Liver Fibrosis in a Sample of Putative Inactive HBV Carriers in Rome, Italy
Table 5
Relation between HBV-DNA and liver stiffness in the subgroup of 66 patients during the follow-up.
Characteristics
HBV-DNA <2000 UI/ml
HBV-DNA ≥2000 UI/ml
value
Basal time
Liver stiffness (kPa)
5.80 ± 2.29
—
—
LS < 7.5 kPa, n (%)
50 (100%)
0 (0%)
—
LS ≥ 7.5 kPa, n (%)
16 (100%)
0 (0%)
12 months
Liver stiffness (kPa)
5.33 ± 1.22
6.79 ± 1.55
<0.001
LS < 7.5 kPa n (%)
47 (87.0%)
7 (13.0%)
<0.001
LS ≥ 7.5 kPa n (%)
4 (33.3%)
8 (66.7%)
24 months
Liver stiffness (kPa)
5.30 ± 1.43
7.69 ± 1.07
<0.0001
LS < 7.5 kPa, n (%)
51 (94.4%)
3 (5.6%)
<0.0001
LS ≥ 7.5 kPa, n (%)
5 (41.7%)
7 (58.3%)
Continuous variable are expressed as mean ± standard deviation (SD). A value <0.05 is considered significant (Wilcoxon test). For categorical variables, a value <0.05 is considered significant (Fisher’s test).