Urea-to-Albumin Ratio and In-Hospital Mortality in Severe Pneumonia Patients

Table 2

Independent predictors of in-hospital mortality by univariate and multivariate Cox regression analyses.

Factors	HR (95% CI)
Univariate Cox analysis
Age	1.013 (1.001–1.026)	0.029
Mechanical ventilation	0.796 (0.641–0.990)	0.040
Vasopressor use	2.407 (1.619–3.578)	<0.001
CRRT	2.402 (1.607–3.592)	<0.001
ALT	1.001 (1.000–1.001)	0.006
Albumin	0.947 (0.908–0.988)	0.011
Urea	1.020 (1.003–1.037)	0.024
AST	1.001 (1.000–1.001)	<0.001
Creatinine	1.002 (1.000–1.003)	0.016
Multivariate Cox analysis
Vasopressor use	1.888 (1.226–2.907)	0.004
CRRT	1.679 (1.020–2.762)	0.041

Covariates included in multivariate analysis: age, sex, mechanical ventilation, vasopressor use, CRRT, ALT, albumin, urea, AST, creatinine. CRRT, continuous renal replacement treatment; ALT, alanine aminotransferase; AST, aspartate aminotransferase; HR, hazard ratio; CI, confidence interval.