A Novel Predictive Model in Recognizing Severe COVID-19 and Multiorgan Injuries: Platelet-to-CRP Ratio
Table 1
Baseline characteristics of included patients, stratified by PC ratio tertiles.
T1 (n = 25)
T2 (n = 25)
T3 (n = 26)
value
Demographics
Age (years)
49.4 ± 11.1
43.3 ± 14.1
41.2 ± 11.9
0.058
Male (%)
14 (56.0)
16 (64.0)
12 (46.2)
0.438
M-S CT performance (%)
21 (84.0)
7 (28.0)
4 (15.4)
<0.001
Highest temperature
38.3 ± 0.6
38.2 ± 0.4
37.9 ± 0.8
0.039
Pulse per minute
93 ± 12
92 ± 11
91 ± 10
0.763
Hypertension (%)
10 (40.0)
4 (16.0)
4 (15.4)
0.064
Fatigue (%)
15 (60.0)
11 (44.0)
11 (42.3)
0.382
Type II diabetes (%)
2 (8.0)
1 (4.0)
1 (3.8)
NA
Hypertension (%)
10 (40.0)
4 (16.0)
4 (15.4)
0.064
GI manifestation
Vomiting (%)
7 (28.0)
4 (16.0)
2 (7.7)
0.154
Diarrhea (%)
8 (32.0)
7 (28.0)
2 (7.7)
0.081
Initial GI involvement (%)
12 (48.0)
9 (36.0)
3 (11.5)
0.017
Respiratory manifestation
Breath (times per minute) (%)
0.466
16
0 (0.0)
0 (0.0)
1 (3.8)
17
0 (0.00)
1 (4.0)
0 (0.0)
18
1 (4.0)
1 (4.0)
3 (11.5)
19
2 (8.0)
3 (12.0)
0 (0.0)
20
16 (64.0)
17 (68.0)
20 (76.9)
21
1 (4.0)
1 (4.0)
1 (3.8)
22
4 (16.0)
2 (8.0)
0 (0.0)
23
1 (4.0)
0 (0.0)
1 (3.8)
Dyspnea (%)
9 (36.0)
4 (16.0)
1 (3.8)
0.012
Cough (%)
17 (68.0)
17 (68.0)
16 (61.5)
0.853
Laboratory characteristics
WBC count (10^9/l)
4.21 ± 1.20
4.60 ± 1.69
4.54 ± 1.56
0.605
Neutrophil count (10^9/l)
2.99 ± 0.85
2.98 ± 1.41
2.82 ± 1.35
0.857
Lymphocyte count (10^9/l)
0.89 ± 0.37
1.21 ± 0.47
1.27 ± 0.60
0.017
Hemoglobulin (g/l)
133.64 ± 14.44
140.00 ± 12.78
135.81 ± 11.25
0.213
Total protein (g/l)
71.00 ± 6.71
69.64 ± 4.62
72.22 ± 5.68
0.284
Globulin (g/l)
31.45 ± 5.30
28.04 ± 3.65
29.69 ± 5.19
0.046
Albumin (g/l)
39.54 ± 3.63
41.60 ± 3.72
42.53 ± 2.27
0.005
Lactic dehydrogenase (U/L)
270.08 ± 83.58
227.36 ± 69.01
183.46 ± 56.63
<0.001
Creatinine (mmol/l)
72.24 ± 19.16
73.73 ± 16.56
66.92 ± 12.81
0.299
Alanine aminotransferase (U/L)
37.24 ± 23.94
29.64 ± 30.62
23.62 ± 20.17
0.162
Aspartate transaminase (U/L)
41.84 ± 26.89
31.64 ± 22.55
24.65 ± 9.60
0.016
Total bilirubin (mmol/l)
15.20 ± 9.43
14.48 ± 9.39
14.84 ± 6.53
0.957
qRT-PCR on stool (%)
6 (24.0)
9 (36.0)
2 (7.7)
0.051
Note. qRT-PCR: quantitative real-time polymerase chain reaction; GI: gastrointestinal; PC ratio: platelet-to-C-reactive protein ratio; PC ratio tertile 1 ≤ 7.60; 7.60 PC ratio tertile 2 ≤ 25.44; PC ratio tertile 3 > 25.44. M-S CT performance: moderate-to-severe computed tomography performance. NA: not applicable. Data are presented as means ± SD, or n (%).
