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Molecular and Epidemiological Trend of Diarrheal Diseases (Acute Gastroenteritis) in Recent Years

Call for Papers

Diarrheal diseases (acute gastroenteritis) represent a major worldwide public health problem particularly in developing countries as well as developed countries. Acute gastroenteritis is a very common disease in young children. It is characterized by massive inflammation of the gastrointestinal tract membranes, leading to frequent vomiting and/or diarrhea. Although regarded as a short-term intestinal disorder, acute gastroenteritis can cause severe dehydration, leading to further complications and hospitalization. Each year, at least, four million children under five years of age die from diarrhea. Some viruses (Rotavirus, Norovirus, Sapovirus, human astrovirus, adenovirus, Aichivirus, etc.) and some bacterial species (Vibrio cholerae, ETEC, Campylobacter, Salmonella, etc.) are the most common identified infectious agents responsible for diarrhea in young children worldwide. Enteric viruses are recognized as the most significant etiological agent of acute gastroenteritis, accounting for approximately 70% of episode.

Despite much progress in the understanding of pathogenesis and of management with the widespread use of oral rehydration therapies, diarrheal illness remains one of the most important causes of global childhood mortality and morbidity.

For this special issue, we solicit high-quality original research articles as well as review articles for investigating diarrheal diseases, molecular and epidemiological trend of diarrheal disease, pathogen-host interaction, and preventable measures.

Potential topics include but are not limited to the following:

  • Changing epidemiological (basic and molecular epidemiology) trend of diarrheal diseases
  • Genetic evolution and recombination of diarrhea causing microorganisms
  • Rapid molecular detection methods (immunochromatography kits, ELISA, multiplex PCR, real-time PCR, partial sequencing, next generation sequencing, etc.)
  • Vaccine targets and potential vaccine candidates for preventing diarrheal diseases
  • Preventive measures

Authors can submit their manuscripts through the Manuscript Tracking System at

Submission DeadlineFriday, 1 June 2018
Publication DateOctober 2018

Papers are published upon acceptance, regardless of the Special Issue publication date.

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