PET Imaging of FSHR Expression in Tumors with ⁶⁸Ga-Labeled FSH1 Peptide

Figure 6

In vivo PET imaging of PC-3 xenografted mice with [⁶⁸Ga] Ga-NOTA-MAL-FSH1. Decay-corrected whole-body coronal MicroPET images of PC-3 tumor bearing mice at 30, 60, and 120 min after injection of 3.7 MBq [⁶⁸Ga] Ga-NOTA-MAL-FSH1 without (a) and with (c) blocking dose. Tumors are indicated by arrows. Quantification of [⁶⁸Ga] Ga-NOTA-MAL-FSH1 in PC-3 tumor, liver, kidneys, and muscle without (b) and with (d) blocking dose. ROIs are shown as mean % ID/g ± SD.

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