CD44v6-Targeted Imaging of Head and Neck Squamous Cell Carcinoma: Antibody-Based Approaches

Figure 1

CD44. (a) Gene map of CD44. Standard CD44 (CD44s) does not contain variable exons. Exons v1–v10 are alternatively spliced. (b) Schematic overview of CD44. CD44 is a transmembrane protein, which consists of a cytoplasmic and extracellular region with hyaluronan binding sites and a variable region. HA: hyaluronic acid; TM: transmembrane region.

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