MR Assessment of Acute Pathologic Process after Myocardial Infarction in a Permanent Ligation Mouse Model: Role of Magnetic Nanoparticle-Contrasted MRI

Figure 4

Comparison of contrasted sizes of MI mice by different MRI methods. The sizes were evaluated by area-based (a) and sector-based approaches (b). Enhancement size of MNP-MRI was significantly larger than that of LGE and MEMRI for both approaches. Difference in the enhancement size between LGE and MEMRI was not significant for both approaches. , , , ns = nonsignificant. (area-based: = 0.34 for LGE versus MEMRI, < 0.0001 for LGE versus MNP-MRI and < 0.0001 for MEMRI versus MNP-MRI; sector-based: = 0.99 for LGE versus MEMRI, = 0.0015 for LGE versus MNP-MRI and = 0.0001 for MEMRI versus MNP-MRI).

(a)

(b)