Table of Contents Author Guidelines Submit a Manuscript
Contrast Media & Molecular Imaging
Volume 2017, Article ID 2870802, 9 pages
https://doi.org/10.1155/2017/2870802
Research Article

MR Assessment of Acute Pathologic Process after Myocardial Infarction in a Permanent Ligation Mouse Model: Role of Magnetic Nanoparticle-Contrasted MRI

1Bio-Imaging Research Team, Korea Basic Science Institute, 161 Yeongudanji-ro, Ochang-eup, Cheongwon-gu, Cheongju 28119, Republic of Korea
2Cardiovascular Center and Division of Cardiovascular Medicine, Seoul St. Mary’s Hospital and College of Medicine, The Catholic University of Korea, 222 Banpo-daero, Seocho-gu, Seoul 06591, Republic of Korea
3Graduate School of Analytical Science and Technology, Chungnam National University, 99 Daehak-ro, Yuseong-gu, Daejeon 34134, Republic of Korea
4Immunotherapy Convergence Research Center, Korea Research Institute of Bioscience and Biotechnology, 125 Gwahak-ro, Yuseong-gu, Daejeon 34141, Republic of Korea
5Department of Biomolecular Science, University of Science and Technology (UST), 217 Gajeong-ro, Yuseong-gu, Daejeon 34113, Republic of Korea
6Laboratory Animal Center, Korea Research Institute of Bioscience and Biotechnology, 125 Gwahak-ro, Yuseong-gu, Daejeon 34141, Republic of Korea

Correspondence should be addressed to Kiyuk Chang; rk.ca.cilohtac@kuyik and Kwan Soo Hong; rk.er.isbk@gnohsk

Received 28 March 2017; Revised 27 August 2017; Accepted 14 September 2017; Published 18 October 2017

Academic Editor: Anne Roivainen

Copyright © 2017 Cheongsoo Park et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. K. Reddy, A. Khaliq, and R. J. Henning, “Recent advances in the diagnosis and treatment of acute myocardial infarction,” World Journal of Cardiology, vol. 7, no. 5, pp. 243–276, 2015. View at Publisher · View at Google Scholar
  2. J. P. Hellermann, S. J. Jacobsen, M. M. Redfield, G. S. Reeder, S. A. Weston, and V. L. Roger, “Heart failure after myocardial infarction: Clinical presentation and survival,” European Journal of Heart Failure, vol. 7, no. 1, pp. 119–125, 2005. View at Publisher · View at Google Scholar · View at Scopus
  3. C. Wang, S. X. Wang, P. S. Dong et al., “Pathological observation of acute myocardial infarction in Chinese miniswine,” International Journal of Clinical and Experimental Pathology, vol. 8, no. 11, pp. 20829–20836, 2015. View at Google Scholar
  4. A. Bonaventura, F. Montecucco, and F. Dallegri, “Cellular recruitment in myocardial ischaemia/reperfusion injury,” European Journal of Clinical Investigation, vol. 46, no. 6, pp. 590–601, 2016. View at Publisher · View at Google Scholar · View at Scopus
  5. M. Nahrendorf, F. K. Swirski, E. Aikawa et al., “The healing myocardium sequentially mobilizes two monocyte subsets with divergent and complementary functions,” The Journal of Experimental Medicine, vol. 204, no. 12, pp. 3037–3047, 2007. View at Publisher · View at Google Scholar · View at Scopus
  6. S. Frantz and M. Nahrendorf, “Cardiac macrophages and their role in ischemic heart disease,” Cardiovascular Research, vol. 102, no. 2, pp. 240–248, 2014. View at Publisher · View at Google Scholar
  7. P. Christia and N. G. Frangogiannis, “Targeting inflammatory pathways in myocardial infarction,” European Journal of Clinical Investigation, vol. 43, no. 9, pp. 986–995, 2013. View at Publisher · View at Google Scholar · View at Scopus
  8. B. Jiang and R. Liao, “The paradoxical role of inflammation in cardiac repair and regeneration,” Journal of Cardiovascular Translational Research, vol. 3, no. 4, pp. 410–416, 2010. View at Publisher · View at Google Scholar · View at Scopus
  9. N. G. Frangogiannis, “Regulation of the inflammatory response in cardiac repair,” Circulation Research, vol. 110, no. 1, pp. 159–173, 2012. View at Publisher · View at Google Scholar · View at Scopus
  10. N. K. Naresh, T. Ben-Mordechai, J. Leor, and F. H. Epstein, “Molecular Imaging of Healing After Myocardial Infarction,” Current Cardiovascular Imaging Reports, vol. 4, no. 1, pp. 63–76, 2011. View at Publisher · View at Google Scholar · View at Scopus
  11. T. Wollenweber, P. Roentgen, A. Schäfer et al., “Characterizing the inflammatory tissue response to acute myocardial infarction by clinical multimodality noninvasive imaging,” Circulation: Cardiovascular Imaging, vol. 7, no. 5, pp. 811–818, 2014. View at Publisher · View at Google Scholar · View at Scopus
  12. C. Rischpler, R. J. Dirschinger, S. G. Nekolla et al., “Prospective Evaluation of 18F-Fluorodeoxyglucose Uptake in Postischemic Myocardium by Simultaneous Positron Emission Tomography/Magnetic Resonance Imaging as a Prognostic Marker of Functional Outcome,” Circulation: Cardiovascular Imaging, vol. 9, no. 4, p. e004316, 2016. View at Publisher · View at Google Scholar · View at Scopus
  13. F. M. Bengel, “Imaging of Post-Infarct Inflammation: Moving Forward Toward Clinical Application,” Circulation: Cardiovascular Imaging, vol. 9, no. 4, 2016. View at Publisher · View at Google Scholar · View at Scopus
  14. P. Camici, L. I. Araujo, and T. Spinks, “Increased uptake of 18F-fluorodeoxyglucose in postischemic myocardium of patients with exercise-induced angina,” Circulation, vol. 74, no. 1, pp. 81–88, 1986. View at Publisher · View at Google Scholar · View at Scopus
  15. D. E. Sosnovik, M. Nahrendorf, N. Deliolanis et al., “Fluorescence tomography and magnetic resonance imaging of myocardial macrophage infiltration in infarcted myocardium in vivo,” Circulation, vol. 115, no. 11, pp. 1384–1391, 2007. View at Publisher · View at Google Scholar · View at Scopus
  16. U. Flogel, Z. Ding, and H. Hardung, “In vivo monitoring of inflammation after cardiac and cerebral ischemia by fluorine magnetic resonance imaging,” Circulation, vol. 118, no. 2, pp. 140–148, 2008. View at Publisher · View at Google Scholar · View at Scopus
  17. F. Bönner, C. Jacoby, S. Temme et al., “Multifunctional MR monitoring of the healing process after myocardial infarction,” Basic Research in Cardiology, vol. 109, no. 5, 2014. View at Publisher · View at Google Scholar · View at Scopus
  18. Y. Yang, Y. Yang, N. Yanasak, A. Schumacher, and T. C.-C. Hu, “Temporal and noninvasive monitoring of inflammatory-cell infiltration to myocardial infarction sites using micrometer-sized iron oxide particles,” Magnetic Resonance in Medicine, vol. 63, no. 1, pp. 33–40, 2010. View at Publisher · View at Google Scholar · View at Scopus
  19. H. Moon, H. E. Park, J. Kang et al., “Noninvasive assessment of myocardial inflammation by cardiovascular magnetic resonance in a rat model of experimental autoimmune myocarditis,” Circulation, vol. 125, no. 21, pp. 2603–2612, 2012. View at Publisher · View at Google Scholar · View at Scopus
  20. J. Takagawa, Y. Zhang, M. L. Wong et al., “Myocardial infarct size measurement in the mouse chronic infarction model: Comparison of area- and length-based approaches,” Journal of Applied Physiology, vol. 102, no. 6, pp. 2104–2111, 2007. View at Publisher · View at Google Scholar · View at Scopus
  21. M. Lichtenauer, C. Schreiber, C. Jung et al., “Myocardial infarct size measurement using geometric angle calculation,” European Journal of Clinical Investigation, vol. 44, no. 2, pp. 160–167, 2014. View at Publisher · View at Google Scholar · View at Scopus
  22. P. Jynge, H. Brurok, A. Asplund, R. Towart, H. Refsum, and J. O. G. Karlsson, “Cardiovascular safety of MnDPDP and MnCl2,” Acta Radiologica, vol. 38, no. 4, pp. 740–749, 1997. View at Publisher · View at Google Scholar · View at Scopus
  23. K. Skårdal, N. P. L. Rolim, O. Haraldseth, P. E. Goa, and M. Thuen, “Late gadolinium enhancement in the assessment of the infarcted mouse heart: A longitudinal comparison with manganese-enhanced MRI,” Journal of Magnetic Resonance Imaging, vol. 38, no. 6, pp. 1388–1394, 2013. View at Publisher · View at Google Scholar · View at Scopus
  24. M.-C. Toufektsian, Z. Yang, K. M. Prasad et al., “Stimulation of A2A-adenosine receptors after myocardial infarction suppresses inflammatory activation and attenuates contractile dysfunction in the remote left ventricle,” American Journal of Physiology-Heart and Circulatory Physiology, vol. 290, no. 4, pp. H1410–H1418, 2006. View at Publisher · View at Google Scholar · View at Scopus
  25. H. Kanamori, G. Takemura, K. Goto et al., “Autophagy limits acute myocardial infarction induced by permanent coronary artery occlusion,” American Journal of Physiology-Heart and Circulatory Physiology, vol. 300, no. 6, pp. H2261–H2271, 2011. View at Publisher · View at Google Scholar · View at Scopus
  26. E. McAlindon, M. Pufulete, C. Lawton, G. D. Angelini, and C. Bucciarelli-Ducci, “Quantification of infarct size and myocardium at risk: evaluation of different techniques and its implications,” European Heart Journal—Cardiovascular Imaging, vol. 16, no. 7, pp. 738–746, 2015. View at Publisher · View at Google Scholar
  27. J. Rajewska-Tabor, M. Pyda, A. Kociemba, M. Janus, M. Lanocha, and A. Siniawski, “Influence of inflammatory response on infarct size and microvascular obstruction estimated by cardiac magnetic resonance in patients with ST-elevation myocardial infarction,” Journal of Cardiovascular Magnetic Resonance, pp. 1-2, 2015. View at Publisher · View at Google Scholar · View at Scopus
  28. N. Ruparelia, J. Godec, R. Lee et al., “Acute myocardial infarction activates distinct inflammation and proliferation pathways in circulating monocytes, prior to recruitment, and identified through conserved transcriptional responses in mice and humans,” European Heart Journal, vol. 36, no. 29, pp. 1923–1934, 2015. View at Publisher · View at Google Scholar · View at Scopus
  29. M. Wildgruber, I. Bielicki, M. Aichler et al., “Assessment of myocardial infarction and postinfarction scar remodeling with an elastin-specific magnetic resonance agent,” Circulation: Cardiovascular Imaging, vol. 7, no. 2, pp. 321–329, 2014. View at Publisher · View at Google Scholar · View at Scopus
  30. J. N. Oshinski, Z. Yang, J. R. Jones, J. F. Mata, and B. A. French, “Imaging time after Gd-DTPA injection is critical in using delayed enhancement to determine infarct size accurately with magnetic resonance imaging,” Circulation, vol. 104, no. 23, pp. 2838–2842, 2001. View at Publisher · View at Google Scholar · View at Scopus
  31. D. S. Fieno, R. J. Kim, E.-L. Chen, J. W. Lomasney, F. J. Klocke, and R. M. Judd, “Contrast-enhanced magnetic resonance imaging of myocardium at risk: Distinction between reversible and irreversible injury throughout infarct healing,” Journal of the American College of Cardiology, vol. 36, no. 6, pp. 1985–1991, 2000. View at Publisher · View at Google Scholar · View at Scopus
  32. P. D. Verdouw, M. A. Van Den Doel, S. De Zeeuw, and D. J. Duncker, “Animal models in the study of myocardial ischaemia and ischaemic syndromes,” Cardiovascular Research, vol. 39, no. 1, pp. 121–135, 1998. View at Publisher · View at Google Scholar · View at Scopus
  33. S. Hashmi and S. Al-Salam, “Acute myocardial infarction and myocardial ischemia-reperfusion injury: a comparison,” International Journal of Clinical and Experimental Pathology, vol. 8, no. 8, pp. 8786–8796, 2015. View at Google Scholar