Table 1

ApplicationsPopulation/Animal modelsRadioligandMain findingsRef.

Preclinical(i) TSPO PET on day 8 after DSS- and TNBS-induced IBD in rats
(ii) 6 rats were followed up over 22 days
18F-DPA-714(i) Significantly increased tracer uptake in the rat colon in both groups, DSS and TNBS, compared to controls
(ii) Increased tracer binding until day 8/10 then tracer uptake decreased slowly
Bernards et al. (2014) [25]

DSS, dextran sodium sulfate; IBD, inflammatory bowel disease; TNBS, trinitrobenzenesulfonic acid.