Kinetic Modelling of Infection Tracers [¹⁸F]FDG, [⁶⁸Ga]Ga-Citrate, [¹¹C]Methionine, and [¹¹C]Donepezil in a Porcine Osteomyelitis Model

Figure 10

First-pass uptake as a function of plasma perfusion, shown along with the identity line (). The black squares represent infection foci and the grey circles represent the corresponding noninfected positions. The plots include both bone and soft tissue data. The data for [⁶⁸Ga]Ga-citrate did not correlate with perfusion ( = 0.03). For [¹¹C]donepezil, all data points are above the identity line, paradoxically corresponding to an extraction fraction above 100%. See Discussion.

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