Use of Ultrasmall Superparamagnetic Iron Oxide Enhanced Susceptibility Weighted Imaging and Mean Vessel Density Imaging to Monitor Antiangiogenic Effects of Sorafenib on Experimental Hepatocellular Carcinoma

Figure 1

Unenhanced and ultrasmall superparamagnetic iron oxide (USPIO) enhanced -weighted and mapping with superimposed region of interest in xenograft hepatocellular carcinoma. (a) Unenhanced -weighted image (tumor signal intensity = 354.2). (b) Unenhanced mapping (tumor = 48 ms). (c) USPIO-enhanced -weighted image (tumor signal intensity = 305.9). (d) USPIO-enhanced mapping (tumor = 24.7 ms).

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