Spectral Photon-Counting Molecular Imaging for Quantification of Monoclonal Antibody-Conjugated Gold Nanoparticles Targeted to Lymphoma and Breast Cancer: An <i>In Vitro</i> Study

<table class="table-group" id="tab2"><tr><td><table class="table"><tr><td class="thead-hr" colspan="2"><hr/></td></tr><tr class="thead"><td class="align_left">Raji phantom</td><td class="align_center">SKBR3 phantom</td></tr><tr><td class="thead-hr" colspan="2"><hr/></td></tr><tr><td class="align_left">AuNPs 2, 4, and 8 mg/mL</td><td class="align_center" rowspan="3">AuNPs 2, 4, and 8 mg/mL</td></tr><tr><td class="align_left">AuNPs size by DLS: 50 nm (expected 40 nm)</td></tr><tr><td class="align_left">AuNPs absorbance: 530 nm</td></tr><tr><td class="align_left">Water, lipid</td><td class="align_center">Water, lipid</td></tr><tr><td class="align_left">Raji cells with Her-AuNP (control)</td><td class="align_center">SKBR3 with Her-AuNP</td></tr><tr><td class="align_left">Raji cells with Rit-AuNP</td><td class="align_center">SKBR3 with Rit-AuNP (control)</td></tr><tr class="table-tr"><td colspan="2"><hr class="tbody-hr"/></td></tr></table></td></tr><tr class="table-fn"><td><div>Her, trastuzumab or Herceptin; Rit, rituximab.<br/></div></td></tr></table>

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Table 2

Table 2: Spectral Photon-Counting Molecular Imaging for Quantification of Monoclonal Antibody-Conjugated Gold Nanoparticles Targeted to Lymphoma and Breast Cancer: An <i>In Vitro</i> Study 

Table 2 | Spectral Photon-Counting Molecular Imaging for Quantification of Monoclonal Antibody-Conjugated Gold Nanoparticles Targeted to Lymphoma and Breast Cancer: An In Vitro Study 