Research Article

Presaturation Power Adjusted Pulsed CEST: A Method to Increase Independence of Target CEST Signals

Figure 8

The temporal changes in the CEST signals at 3.0 ppm in the renal medulla are shown over 0 to 30 min after injection of Glu plus either low-Nic (a) and high-Nic (b) solutions. All CEST signals peaked at 10 min and decreased nearly back to baseline levels at 30 min after both injections. Although the injected dose of Glu was the same in both cases, the CEST signal was higher in the high-Nic group compared to that in the low-Nic group. By contrast, the subtracted CEST images showed similar levels of the CEST signals at all time points between the two injection groups (green lines). and .
(a)
(b)