Research Article

Dynamic Contrast-Enhanced Imaging as a Prognostic Tool in Early Diagnosis of Prostate Cancer: Correlation with PSA and Clinical Stage

Table 2

Comparison of the 62 patients with peripheral and transitional zone prostate cancer (46 versus 16): age, tumor size, and DWI- and DCE-derived tumor parameters.

Total mean ± SDPeripheral mean ± SDTransitional mean ± SD value

Age (years)70 ± 570 ± 570 ± 40.974
PSA (ng/mL)9.5 ± 3.79.7 ± 3.99.1 ± 3.30.552
Area of tumor (cm2)0.74 ± 0.470.68 ± 0.410.93 ± 0.590.037
ADC (×10−3 mm2/s)0.87 ± 0.160.89 ± 0.170.82 ± 0.130.259
Ktrans (min−1)0.15 ± 0.050.15 ± 0.050.14 ± 0.060.743
Kep (min−1)0.57 ± 0.220.59 ± 0.210.49 ± 0.240.048
Ve0.28 ± 0.080.27 ± 0.080.32 ± 0.070.026
iAUC (mmoL/L/min)16.70 ± 5.6917.26 ± 5.5115.86 ± 6.210.626

PSA, prostate-specific antigen; ADC, apparent diffusion coefficient; Ktrans, volume transfer constant; Kep, reflux constant; Ve, extravascular extracellular leakage volume fraction; iAUC, initial area under curve; n, number of tumors.