Contrast Media & Molecular Imaging / 2018 / Article / Fig 1

Research Article

Exposure of Macrophages to Low-Dose Gadolinium-Based Contrast Medium: Impact on Oxidative Stress and Cytokines Production

Figure 1

Cell viability of different types of gadolinium-based contrast agents (GBCAs) and gadolinium chloride on RAW 264.7 cells. Macrophages (RAW 264.7) were incubated in the absence or presence of 0.25, 0.83, and 2.5 µM/mL of various GBCAs or Gd chloride for 24 h. The pH values of PBS diluted GBCAs were checked (a) (n = 3). The effect of GBCAs or Gd chloride on cell viability was determined by MTT assays immediately after incubation (b, c) (n = 3). Representative morphology recorded with a microscope after treatment with GBCAs for 24 h (d).

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