Contrast Media & Molecular Imaging / 2018 / Article / Fig 3

Research Article

Exposure of Macrophages to Low-Dose Gadolinium-Based Contrast Medium: Impact on Oxidative Stress and Cytokines Production

Figure 3

The effects of the different GBCAs and gadolinium chloride-induced reactive oxidative species and mitochondrial membrane potential in cultured RAW 264.7. The production of ROS was measured after treatment with 2.5 μM Gd chloride or GBCAs for 4 h (a) and 24 h (b). Similarly, mitochondrial membrane potential was measured after 4 h (c) and 24 h (d) of treatment. when compared with the control, # when compared with Gd chloride. Positive control, H2O2 (2000 μM) for 30 min.
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