Sensitivity of Multiphase Pseudocontinuous Arterial Spin Labelling (MP pCASL) Magnetic Resonance Imaging for Measuring Brain and Tumour Blood Flow in Mice

<div>Application of the MP pCASL sequence in mice with intracerebral 4T1-GFP metastatic tumours showing gadolinium enhancement. (a) <i>T</i><sub>1</sub>-weighted image showing enhancement (dotted outline) of metastatic foci. (b) CBF maps with the same ROI indicated. (c) Graph showing CBF values in tumour and contralateral regions; no significant decrease in perfusion is evident (d-e). Histological comparison of microvessel area fraction in tumour (d), and contralateral (e) regions. Scale bars = 20 <i>µ</i>m. 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Contrast Media & Molecular Imaging

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Figure 5

Figure 5: Sensitivity of Multiphase Pseudocontinuous Arterial Spin Labelling (MP pCASL) Magnetic Resonance Imaging for Measuring Brain and Tumour Blood Flow in Mice 

Figure 5 | Sensitivity of Multiphase Pseudocontinuous Arterial Spin Labelling (MP pCASL) Magnetic Resonance Imaging for Measuring Brain and Tumour Blood Flow in Mice 