Light-Triggered Radiochemical Synthesis: A Novel 18F-Labelling Strategy Using Photoinducible Click Reaction to Prepare PET Imaging Probes

<div>(a) PET/CT images of 18FB-PEGHc-RGD ([18F]8) in RR1022 tumor-bearing rats at 1 h and 2 h after injection. High radioactivity accumulations were found in the tumor (red arrow) at 1 h and 2 h after injection of 18FB-PEGHc-RGD ([18F]8). Inhibition study using nonradiolabelled c(RGDyK) showed complete blocking of radioactivity in the tumor. (b) Transaxial views showing high tumor uptake of 18FB-PEGHc-RGD ([18F]8).</div>

Contrast Media & Molecular Imaging

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Figure 4

Figure 4: Light-Triggered Radiochemical Synthesis: A Novel 18F-Labelling Strategy Using Photoinducible Click Reaction to Prepare PET Imaging Probes