Research Article

Multiparametric FDG-PET/MRI of Hepatocellular Carcinoma: Initial Experience

Figure 1

A 56-year-old male patient with cirrhosis secondary to chronic HCV and HCC. DCE-MRI, IVIM (b = 400), and BOLD (TE = 30 ms, pre-O2) images and PET overlay on anatomical T2-weighted image demonstrate 2.7 cm HCC in the right liver lobe (white arrows). Plots of the DCE-MRI, IVIM, and BOLD data points (open circles) and fits (solid lines; SSM fit shown for DCE-MRI) are displayed in the panels at the bottom of the figure for liver (blue) and HCC (red) ROIs. The fitted parameters are shown next to the plots. The HCC lesion showed nonavid FDG uptake (SUVmean 1.57 and SUVmax 1.99) and high perfusion/permeability as measured by DCE-MRI.