Research Article

Multimodal PET/MRI Imaging Results Enable Monitoring the Side Effects of Radiation Therapy

Figure 3

The effect of irradiation on brain [18F]FDG uptake values. The mean SUVs of the left (irradiated) brain regions (Th: thalamus; Ctx: cortex; Hth: hypothalamus; Hc: hippocampus; Cb: cerebellum; Amy: amygdala; Str: striatum) are shown at five different time points by 5 Gy (a) and 20 Gy (b) dose groups.The boxplots show median with quartiles, minimum, and maximum. Correlation maps of [18F]FDG uptake values of the left versus right brain areas (regardless of the time points) by 5 Gy (c) and 20 Gy (d) dose groups are shown. The heat maps visualize the Pearson correlation of irradiation effects between each investigated brain region. The time trend analysis of the whole brain is shown in (e).
(a)
(b)
(c)
(d)
(e)