Standardized Uptake Values Derived from ¹⁸F-FDG PET May Predict Lung Cancer Microvessel Density and Expression of KI 67, VEGF, and HIF-1α but Not Expression of Cyclin D1, PCNA, EGFR, PD L1, and p53

Table 1

Methodological quality of the involved 40 studies according to the QUADAS criteria.

QUADAS criteria	Yes (%)	No (%)	Unclear (%)
Patient spectrum	38 (95.0)	—	2 (5.0)
Selection criteria	28 (70.0)	1 (2.50)	11 (27.5)
Reference standard	40 (100)	—	—
Disease progression bias	40 (100)	—	—
Partial verification bias	40 (100)	—	—
Differential verification bias	40 (100)	—	—
Incorporation bias	40 (100)	—	—
Text details	40 (100)	—	—
Reference standard details	40 (100)	—	—
Text review details	16 (40.0)	4 (10.0)	20 (50.0)
Diagnostic review bias	17 (42.5)	4 (10.0)	19 (47.5)
Clinical review bias	39 (97.5)	—	1 (2.5)
Uninterpretable results	39 (97.5)	—	1 (2.5)
Withdrawal explained	38 (95.0)	1 (2.5)	1 (2.5)