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Contrast Media & Molecular Imaging
Volume 2018, Article ID 9713691, 24 pages
https://doi.org/10.1155/2018/9713691
Review Article

Prospective of 68Ga Radionuclide Contribution to the Development of Imaging Agents for Infection and Inflammation

1Section of Nuclear Medicine and PET, Department of Surgical Sciences, Uppsala University, Uppsala, Sweden
2Preclinical PET Platform, Department of Medicinal Chemistry, Uppsala University, Uppsala, Sweden
3PET Centre, Centre for Medical Imaging, Uppsala University Hospital, 75185 Uppsala, Sweden

Correspondence should be addressed to Irina Velikyan; es.aksimedaka@naykilev.aniri

Received 17 September 2017; Revised 19 November 2017; Accepted 10 December 2017; Published 4 January 2018

Academic Editor: Xiang-Guo Li

Copyright © 2018 Irina Velikyan. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

During the last decade, the utilization of 68Ga for the development of imaging agents has increased considerably with the leading position in the oncology. The imaging of infection and inflammation is lagging despite strong unmet medical needs. This review presents the potential routes for the development of 68Ga-based agents for the imaging and quantification of infection and inflammation in various diseases and connection of the diagnosis to the treatment for the individualized patient management.