Review Article

Prospective of 68Ga Radionuclide Contribution to the Development of Imaging Agents for Infection and Inflammation

Figure 8

Schematic presentation of pretargeting techniques: (a) bispecific antibodies engineered to specifically bind with radiolabelled hapten molecules; (b) bioorthogonal click chemistry for fast and specific covalent binding between, for example, a trans-cyclooctene functionalized antibody and a radiolabelled tetrazine; (c) interaction between antibody-(strept)avidin conjugate and radiolabelled biotin utilizing extremely high affinity of (strept)avidin and biotin.
(a)
(b)
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