A Comparative Study of Two-Compartment Exchange Models for Dynamic Contrast-Enhanced MRI in Characterizing Uterine Cervical Carcinoma

Table 3

Comparison of model parameters between cervix carcinoma and normal cervix tissue.

	Fp (mL/min/100 mL)	Vp (mL/100 mL)	Ve (mL/100 mL)	PS (mL/min/100 mL)
AATH-normal cervix	44.57 ± 23.23	1.27 ± 1.25	32.15 ± 14.32	10.40 ± 6.43
AATH- cervix cancer	34.13 ± 15.15	2.55 ± 2.30	17.03 ± 10.80	8.88 ± 4.28
	<0.001^a	<0.001^a	<0.05^a	>0.05^a
AUC	0.67	0.75	0.85	0.56
SC-normal cervix	19.51 ± 15.96	6.00 ± 7.65	29.95 ± 17.33	11.14 ± 7.18
SC-cervix cancer	18.48 ± 7.31	6.80 ± 4.24	19.21 ± 20.05	6.21 ± 4.40
	>0.05^b	<0.001^a	<0.001^a	<0.001^a
AUC	0.50	0.64	0.75	0.75
DP-normal cervix	16.06 ± 21.22	4.90 ± 3.24	31.88 ± 18.41	9.67 ± 5.62
DP-cervix cancer	14.83 ± 5.23	4.38 ± 3.06	16.05 ± 13.34	8.13 ± 3.96
	<0.01^a	>0.05^b	<0.001^a	<0.05^a
AUC	0.60	0.54	0.83	0.58

AUC, area under the ROC curve. ^aComparison was performed by the Mann–Whitney U test. ^bComparison was performed by the independent t test.