Research Article

Prediction of Chemotherapy Response of Osteosarcoma Using Baseline 18F-FDG Textural Features Machine Learning Approaches with PCA

Table 1

Index of textural features in global, local, and regional areas.

Feature familyFeatures

Intensity histogramSUVmax
SUVmean
Standard deviation
Total lesion glycolysis (TLG)
Metabolic tumor volume (MTV)
1st entropy

Gray level co-occurrence matrix (GLCM)Energy
Contrast
Entropy
Homogeneity
Dissimilarity

Neighboring gray level dependence matrix (NGLDM)Small number emphasis
Large number emphasis
Coarseness
Busyness

Gray level run length matrix (GLRLM)Short run emphasis
Long run emphasis
Gray level nonuniformity
Run length nonuniformity
Low gray level run emphasis
High gray level run emphasis

Gray level size zone matrix (GLSZM)Small zone emphasis
Large zone emphasis
Gray level nonuniformity
Zone size nonuniformity
Low gray level zone emphasis
High gray level zone emphasis