Table 3: Parameters used in each differential model.

MethodParameters

SUV metricsSUVmax

CT predicted variableHISTO_kurtosisSHAPE_volume (mL)
GLCM_homogeneityGLRLM_RLNU
NGLDM_busynessGLZLM_LZHGE

PET predicted variableHISTO_entropy_log10SHAPE_volume(# vx)
GLCM_entropy_log10NGLDM_contrast
GLRLM_HGRE GLZLM_HGZE

Combination of PET and CT texture parametersHISTO_kurtosisSHAPE_volume (mL)
GLCM_homogeneityGLRLM_RLNU
NGLDM_busynessGLZLM_LZHGE
HISTO_entropy_log10SHAPE_volume(# vx)
GLCM_entropy_log10NGLDM_contrast
GLRLM_HGREGLZLM_HGZE

Abbreviations: HISTO, histogram; GLCM, gray-level co-occurrence matrix; GLRLM, gray-level run-length matrix; HGRE, high gray-level run emphasis; GLZLM, gray-level zone-length matrix; HGZE, high gray-level zone emphasis; RLNU, run-length nonuniformity; LZHGE, long-zone high gray-level emphasis.