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Figure 5: (a) Micro-PET images of [18F]FP-D-Lys6-GnRH in nude mice bearing PC-3 and SKBR-3 tumors at 60 min after intravenous injection. (b) MicroPET/CT images of [18F]FP-D-Lys6-GnRH in nude mice bearing the PC-3 tumor at 5, 15, 30, 60, 90, and 120 min after intravenous injection for control and blocking groups. Images are shown in coronal views. Tumors are indicated by arrowheads. (c) Time-activity curves illustrate [18F]FP-D-Lys6-GnRH dynamics in selected ROIs. (d) Comparison of the tumor to muscle and heart ratios of [18F]FP-D-Lys6-GnRH in nude mice bearing PC-3 tumors from 0 to 120 min after intravenous injection for control and blocking groups (/group). T: tumor; M: muscle; H: heart.