Review Article

Nuclear Imaging of Glucose Metabolism: Beyond 18F-FDG

Figure 3

A novel 99mTc-labeled glucose derivative for SPECT imaging. (a) Chemical structure of 99mTc-CN5DG. Whole-body SPECT/CT images of 99mTc-CN5DG (55 MBq) in nude mice bearing A549 xenografts with a tumor size of 3 mm (b) and 5 mm (c) in diameter at 30 min, 60 min, and 120 min after injection. Adapted from Reference [40] with permission.