Review Article

Preclinical Molecular Imaging for Precision Medicine in Breast Cancer Mouse Models

Figure 3

Dynamic contrast-enhanced (DCE) magnetic resonance imaging (MRI) parametric maps. In (a) Ktrans and in (b) of a representative mouse from each group. The Ktrans parametric maps reveal enhancement along the periphery with increasing trends in the BT474-treated group. The Ktrans parametric maps remain fairly consistent in HR6-treated groups, while the BT474 and HR6 control groups slightly decrease over time. The parametric maps reveal variations within all the observed tumors, with increased levels in the treated groups compared to the control groups (reprinted from [20], copyright with permission from © 2014 Neoplasia Press, Inc., published by Elsevier Inc.).
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